Lab members leaning casually around an eye chart.

Chandna Lab (SEELAB)

Binocular vision, Strabismus, Amblyopia, Cerebral Visual Impairment

Our laboratory investigates mechanisms of normal and abnormal vision and ocular motility in adults and children with special emphasis on neurotypicals, strabismus, amblyopia, cerebral visual impairment, and acquired brain injury. We use visual electrophysiology/EEG methods and measures of eye movements, accommodation with eye trackers, and infrared photorefractor. There is a strong emphasis on translational research in infants and children. We investigate globally common eye diseases in children and in adults associated with long-tem visual loss and morbidity with high socioeconomic costs and impacts. Our aim is to improve detection, diagnosis, treatment and outcomes in childhood eye disease through rigorous scientific research. 

Current projects

Use of non-invasive, quantitative methods, including: low-channel and high-density EEG steady-state visual evoked potentials (SSVEP); eye tracking and photorefraction; and qualitative methods in correlation with clinical findings: 

  • Studying mechanisms of visual function loss in amblyopia and strabismus
  • Exploring low, mid and higher visual function deficits (HVFDs) in children with mild to moderate cerebral visual impairment (CVI) 
  • Developing applications for visual assessment and training in babies and young children.
  • Studying mechanisms of vergence and accommodation in strabismus and other clinical conditions such as mild traumatic brain injury (mTBI).
  • Investigating role ocular dominance, sensor and motor, in oculomotor stability.
  • Reading studies wih simultaneous messures of oculomotor control and accommodaton..
  • Comparing monocular and binocular sensory and motor functions


If you are interested in being a participant or wish to know more about our work, please get in touch with us at seelab@ski.org

We are especially interested in the following eye conditions:

  • Strabismus (misaligned eyes) since childhood
  • Anisometropia (a significant difference in eyeglass prescription between the two eyes) since childhood
  • Amblyopia (poor vision in one or both eyes since childhood often associated with strabismus and anisometropia) 
  • Cataract in childhood 
  • Loss of one eye in childhood

Tabs

  • Collage of RERC staff mebers and RERC projects

    Rehabilitation Engineering Research Center

    The Center's research goal is to develop and apply new scientific knowledge and practical, cost-effective devices to better understand and address the real-world problems of blind, visually impaired, and deaf-blind consumers

    View Center
Active
  • Parent with infant on lap reading a high contrast picture book
    Active

    CVI@SKI Meeting

    We are a Smith-Kettlewell Eye Research Institute sponsored, Blind Babies Foundation supported research advocacy group consisting of SKI researchers, select clinicians, teachers of the visually impaired, and parents of children with cerebral visual impairment.

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  • Illlustration of cover test
    Active

    Eye Movements and Accommodation Patterns in Strabismus

    Strabismus misaligned eyes is a common developmental condition in young children that can lead to amblyopia or poor vision and other forms of low vision. This project looks at the eye movements in relation to accommodation or focusing power in these patients to determine predictors of strabismus and outcome of treatment, with the goal of improving early detection, intervention and treatment.

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  • Schematic drawing of neuro-cognitive model of CVI showing the ventral and dorsal streams
    Active

    Higher Visual Function (HVF) in Individuals with Cerebral Visual Impairment (CVI)

    The purpose of this research study is to learn about how amblyopia, strabismus, and cerebral visual impairment affect the visual system and develop new techniques for assessing visual function in these populations.

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  • Active

    Investigating Reading in Individuals with Cerebral Visual Impairment (CVI)

    In this project, we aim to understand (i) how CVI affects reading, (ii) how current rehabilitation techniques or assistive technologies help improve reading in CVI and (iii) what more can be done to assist those individuals with CVI

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  • Vernier sweep schematic
    Active

    Patterns of Visual Deficits in Amblyopia

    Background Amblyopia means blunted sight in the Greek language and is a term clinicians use to describe decreased vision usually in one eye most commonly due to a focusing error (refractive error in one eye, very different from other eye - anisometropia) and/or a misalignment between the two eyes (strabismus or squint). Amblyopia is sometimes called “lazy eye”. This is different than being just near or far sighted which is a refractive error usually similar and in both eyes developing at any age and vision improves instantly on prescribing and wearing spectacles to correct the error.

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  • Active

    Reading in mTBI

    People with mTBI often complain about dificulty in reading in spite of normal results in usual eye exams.

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Completed
Current
  • Photo of Nick

    In Memoriam: Nikolay Nichiporuk

    The Smith-Kettlewell Eye Research Institute mourns the tragic loss of our young colleague Nikolay (Nick) Nichiporuk, who has tragically and unexpectedly passed away. Nick joined us in July 2019 and worked full time as a Research Assistant in the lab of Dr. Arvind Chandna. Working within this group Nick played a vital role in developing research programs towards investigating vision problems in...
  • Dr. Arvind Chandna

    Dr. Arvind Chandna Receives the PMC Department of Ophthalmology Residency Teaching Award for 2020

    Arvind Chandna , M.D., Senior Clinician Scientist at Smith Kettlewell Eye Research Institute was selected as a recipient of a CPMC Department of Ophthalmology Residency Teaching Award for 2020. This award was presented to him at the Barkan Research Symposium on Saturday, June 13, 2020, via Zoom. Dr. Arvind Chandna is part of the Voluntary Faculty Program for Teaching the Residents at the...
  • Arvind Chandna wins the William and Ruth Silverman Excellence in Community Partnerships Award

    We are very pleased to announce that Dr. Arvind Chandna was awarded The Sliverman Award at the 24th Annual Lowenfeld-Akeson Early Years Symposium (2020) on February 1st. The William and Ruth Silverman Excellence in Community Partnerships award is bestowed to a worthy clinician for outstanding contributions and connections to families of young children with visual impairments by a medical...