Hou Lab
Our research interests include investigating human visual cortex development and brain plasticity associated with amblyopia (lazy eye) and strabismus (misaligned eyes).
Tabs
Journal Articles
. (2022). A novel method for utilizing dichoptic attention tasks in amblyopic training. Methodsx , 9 (101829). Retrieved from https://doi.org/10.1016/j.mex.2022.101829
. (2022). Bilirubin-induced neurotoxicity and visuocortical dysfunction. Journal Of Perinatology, 1–2. http://doi.org/10.1038/s41372-022-01417-2
. (2021). Feature Counting Is Impaired When Shifting Attention Between the Eyes in Adults With Amblyopia. Frontiers In Neuroscience, 15. http://doi.org/doi: 10.3389/fnins.2021.674146
. (2021). Excitatory Contribution to Binocular Interactions in Human Visual Cortex is Reduced in Strabismic Amblyopia. Journal Of Neuroscience. http://doi.org/10.1523/JNEUROSCI.0268-21.2021
. (2020). Feature Counting Under Dichoptic Viewing in Anisometropic and Strabismic Amblyopia. Translational Vision Science & Technology, 9(6), 13-13. http://doi.org/doi:https://doi.org/10.1167/tvst.9.6.13
. (2020). Contrast Normalization Accounts for Binocular Interactions in Human Striate and Extra-striate Visual Cortex. Journal Of Neuroscience, 40(13), 2753-2763.
. (2017). Latent Binocular Interactions in Cortical Area V1 of Human Amblyopia. Journal Of Vision, 17(10), 758-758. http://doi.org/10.1167/17.10.758
. (2016). Degraded attentional modulation of cortical neural populations in strabismic amblyopia. Journal Of Vision, 16, 16.
. (2016). Degraded attentional modulation of cortical neural populations in strabismic amblyopia. Journal Of Vision, 16(3), 1–16.
. (2015). Visuocortical bilirubin-induced neurological dysfunction. Semin Fetal Neonatal Med, 20(1), 37-41.
Presentations/Posters
. (2020). Evidence of Audiovisual Interactions in The Primary Auditory Cortex. presented at the 06/2020, Virtual Vision Science Society.
. (2019). Estimated Counting During Dichoptic Viewing in Amblyopia. presented at the 06/2019, International Conference on Predictive Vision: Toronto, ON.
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Visual Processing and Eye Movements Journal Club
Read MoreThe Visual Processing and Eye Movements Journal Club meets at noon on Tuesdays to discuss developments in the fields of vis
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Visual Processing and Eye Movements Journal Club
Read MoreThe Visual Processing and Eye Movements Journal Club meets at noon on Tuesdays to discuss developments in the fields of vis
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Visual Processing and Eye Movements Journal Club
Read MoreThe Visual Processing and Eye Movements Journal Club meets at noon on Tuesdays to discuss developments in the fields of vis
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Visual Processing and Eye Movements Journal Club
Read MoreThe Visual Processing and Eye Movements Journal Club meets at noon on Tuesdays to discuss developments in the fields of vis
Pages
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Smith-Kettlewell Brain Imaging Center
View CenterThe Smith-Kettlewell Brain Imaging Center supports a wide variety of human brain imaging modalities, including MRI, MRI morphometry, functional MRI, fMR Iretonogrphy, fMRI dynamics, functional connectivity, Granger-causal connectivity, DTI, DTI tractography, whole-head EEG, EEG functional connectivity, ERG, EEG eye tracking, electroblepharography, etc. Our work centers on human visual neuroscience and computational vision, especially in the areas of human visual processing in adults, of the diagnosis of eye diseases and cortical deficits in infants and adults, on brain plasticity in relation to low vision and blindness, and on the processes of blindness rehabilitation. We are particularly interested in the normal capabilities of binocular visual processing and its disruption by forms of traumatic brain injury.
Active
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ActiveAlleviating interocular suppression by high-attention demand training in amblyopia
Read MoreThe goal of this project is to test a hypothesis that whether or not training patients to pay more attention to the input from the amblyopic eye can overcome interocular suppression to treat amblyopia.
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ActiveFellow Eye Deficits in Strabismic Amblyopia
Read MoreFellow eye abnormalities have been reported in a number of psychophysical and VEP studies. The goal of this project is to characterize the fellow eye deficits.
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ActiveGrouping and Perception in Different Types of Amblyopia
Read MoreThis project was to measure the neural correlates of grouping and perception in different types of amblyopia. We found that strabismus generates significant abnormalities at both early and later stages of cortical processing and, importantly, that these abnormalities are independent of visual-acuity deficits
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ActiveThe Role of Selective Visual Attention in Amblyopic Suppression
Read MoreIndividuals with strabismus are confronted with double vision, their brain has to choose to attend to one image and ignore or suppress the other. It has been commonly suggested that a constant suppression on the non-preferred eye in strabismus is responsible for the development of amblyopia. In the current project, we study the role of top-influences of attention in amblyopic suppression and test the hypothesis that visual suppression in amblyopia may be a form of long-term attentional “neglect”.
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Inactive
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Inactive
Neonatal Jaundice and Vision Loss
Read MoreHigh concentrations of unconjugated bilirubin are neurotoxic and cause brain damage in newborn infants. However, the exact level of bilirubin that may be neurotoxic in a given infant is unknown.
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Inactive
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Inactive
Visual Cortical Function in Very Low Birth Weight Infants
Read MorePreterm infants are at high risk of visual and neural developmental deficits. We used swept parameter visual evoked potential (sVEP) to determine whether premature birth alters visual cortical function.
Current
- Audrey Wong-Kee-You - Postdoctoral Fellow
- Julie Freschl - Postdoctoral Fellow
- Margaret McGovern - Participant Coordinator
- Spero Nicholas - Senior Programmer-Analyst
- Zhangziyi Zhou - Research Data Analyst
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Associate Scientist Dr. Chuan Hou Is Awarded a Five-Year Grant from NEI-NIH
Congratulations to Associate Scientist Chuan Hou, MD, PhD, of The Smith-Kettlewell Eye Research Institute in San Francisco, who was awarded a five-year grant for an amblyopia study from the National Eye Institute of the National Institutes of Health. Dr. Hou is a pediatric ophthalmologist with over ten years experience in clinical practice and eye surgeries in strabismus, cataract, glaucoma and...
Principal Investigator:
Contact:
2318 Fillmore St
San Francisco
CA
94115
chuanhou@ski.org
Office:
(415) 345-2073
Lab:
(415) 345-2069
Fax:
(415) 345-8455