SKERI-Optos: A Graphical User Interface to Map Scotoma and PRL with the Optos OCT/SLO

Walker et al (Renninger Psomadakis, Dang & Fletcher, 2008) suggested a novel method to estimate the monocular scotoma area from perimetry data in macular degeneration based on (i) an optic-disc based estimation of the location of the fovea and (ii) the increase in the receptive field size with eccentricity. Here, we introduce a new GUI that applies this method to data from the Optos OCT/SLO. With OCT, it is sometimes possible to locate the foveal pit, giving a better estimation of the fovea. The GUI takes the perimetry, fixation stability and OCT image of each eye as input. It outputs the scotoma area and map relative to the PRL and the estimated fovea. This helps clinicians and researcher to have an objective measure of monocular scotoma and its geometric relation to the PRL and the estimated fovea. The GUI computes BCEA of the PRL and reports the fovea-PRL distance which is valuable information for PRL training. A prediction of the binocular scotoma map/area is computed, assuming that the foveae in the two eyes are aligned. This map informs the user of potential benefits of binocular vision. The GUI has been used by different labs, including ours, at the Smith-Kettlewell Eye Research institute. The GUI is available to the public. A user guide is provided.