My research centers on human visual neuroscience and computational vision, especially in the areas of stereoscopic depth, form, symmetry, and motion perception in adults, and the development of noninvasive tests for the diagnosis of eye diseases in infants and adults. The current focus of the lab is on theoretical, psychophysical, oculomotor and fMRI studies of the integration of cues to the full scope of 3D depth perception. We are particularly interested in the normal capabilities of binocular eye movement control and its disruption by forms of traumatic brain injury.
Smith-Kettlewell Brain Imaging Center
The Smith-Kettlewell Brain Imaging Center supports a wide variety of human brain imaging modalities, including MRI, MRI morphometry, functional MRI, fMR Iretonogrphy, fMRI dynamics, functional connectivity, Granger-causal connectivity, DTI, DTI tractography, whole-head EEG, EEG functional connectivity, ERG, EEG eye tracking, electroblepharography, etc. Our work centers on human visual neuroscience and computational vision, especially in the areas of human visual processing in adults, of the diagnosis of eye diseases and cortical deficits in infants and adults, on brain plasticity in relation to low vision and blindness, and on the processes of blindness rehabilitation. We are particularly interested in the normal capabilities of binocular visual processing and its disruption by forms of traumatic brain injury.
The main areas of my research are learning and brain plasticity of multimodal sensorimotor processing in the blind and the sighted.
Spectral ERG analysis of hypersensitivity to light in traumatic brain injury
The purpose of this research study is to use the spectral electroretinogram (ERG) to deteremine how the retinal mechanisms of sufferers from abnormal light sensitivity due to head injury differ from those without abnormal light sensitivity.
Mechanisms of Photophobia in Mild Traumatic Brain Injury in Human Subjects: Therapeutic Implications
The purpose of this grant is to identify the mechanisms responsible for generating photophobia in patients who have suffered mild traumatic brain injury (mTBI). Currently, estimates indicate that this painful condition persists in about 60% of those who suffered from blast-related traumatic brain injury and 30% of those who suffered non-blast-related concussive injuries.
SL-CN: Harnessing the Power of Drawing for the Enhancement of Learning across Levels of Vision Function
This Science of Learning Collaborative Network brings together researchers and experts from the Smith-Kettlewell Eye Research Institute, University of Bamberg (Germany), Columbia University and Emory University to investigate how the visual art of drawing can enhance learning. Underlying learning principles and neural mechanisms will be considered, and how these can be harnessed for real-life learning enhancement. Though humans have been drawing for at least 30,000 years, little is understood about brain processes involved in this activity.
Harnessing the Power of Drawing for the Enhancement of Learning across Levels of Vision Function
Recent scientific findings about art and drawing suggest that drawing can facilitate learning in a wide variety of domains. The proposed collaboration will develop an interdisciplinary research program aimed at harnessing the power of drawing to enhance learning across fields of intellectual endeavor.
Advanced Spatiomotor Rehabilitation for Navigation in Blindness & Visual Impairment
Successful navigation requires the development of an accurate and flexible mental, or cognitive, map of the navigational space and of the route trajectory required to travel from the current to the target location. The Cognitive-Kinesthetic (C-K) Rehabilitation Training that we have developed in the preceding period utilizes a unique form of blind memory-guided drawing to develop cognitive mapping to a high level of proficiency.
Human Oculomotor Functions & Their Deficits in Traumatic Brain Injury
Recent studies have established that a high proportion of patients diagnosed with mild (or diffuse) traumatic brain injury (mTBI) exhibit binocular vision dysfunctions, particularly, deficiencies in the binocular coordination of eye movements.
Encoding of 3D Structure in the Visual Scene: A New Conceptualization
The multidisciplinary goal was to develop an integrated conceptualization of the mid-level encoding of 3D object structure from multiple surface cues
Advanced Spatiomotor Rehabilitation in Blindness and Visual Impairment
We propose a multidisciplinary approach to effective spatiomotor rehabilitation in blindness and visual impairment. For those who have lost vision, the eye-hand coordination normally available for the manipulation of objects for everyday activities is unavailable and has to be replaced by information from other senses