Chandna Lab (SEELAB)
Arvind Chandna
Senior Clinician-Scientist/Pediatric Ophthalmologist & Adult Strabismus Surgeon
Degrees: M.D. (Doctorate of Medicine, Bristol University. UK)
D.O. (Royal College of Ophthalmologists. UK)
FRCS (Royal College of Surgeons, Edinburgh. UK)
FRCOphth (Royal College of Ophthalmologists. UK)
D.O. (Royal College of Ophthalmologists. UK)
FRCS (Royal College of Surgeons, Edinburgh. UK)
FRCOphth (Royal College of Ophthalmologists. UK)
I am a Senior Clinician Scientist at Smith Kettlewell Eye Research Institute (SKERI) conducting research programmes dealing with significant gaps in clinical and scientific knowledge of common childhood eye conditions with poor management outcomes, and investigate them in collaboration with SKERI’s vision scientists. I have put together some of the clinical challenges as research questions to be investigated with a view to improving diagnosis and intervention and ultimately resulting in improved patient outcomes.
My main interests are to determine the relationship of accommodation and vergence in strabismus; assessment of patterns of visual function loss in amblyopia and cerebral visual impairment. My research programmes investigate visual brain neuroscience and oculomotor behavior using eye tracking, photorefraction, psychophysics and visually evoked brain potentials in childhood eye disease.
I work with a team of young scientists and collaborate with senior scientists both a SK ad other laboratories; children and parents of affected children; and teachers of the visually impaired children with specific expertise in the areas of investigation. such as amblyopia, strabismus, cerebral visual impairment childhood cataract and visual function in children who are monocular.
Previously, I worked for 25 years as a Consultant Pediatric Ophthalmologist and Strabismus Surgeon at Alder Hey Children’s Hospital, Liverpool, UK. My clinical training was at university teaching hospitals in Delhi, London, Manchester, Bristol, Miami and San Francisco. My research training at Bristol University was in application of preferential looking techniques in of normal and abnormal visual development. I completed my pediatric ophthalmology and strabismus fellowship at Bascom Palmer in Miami and Smith Kettlewell Eye Research Institute (SKERI) in San Francisco.
Tabs
Journal Articles
. (2019). Differential Experience-Dependent Plasticity of Form and Motion Mechanisms in Anisometropic Amblyopia. Investigative Opthalmology & Visual Science, 60, 4109. http://doi.org/10.1167/iovs.19-27005 (Original work published 2019)
. (2019). Calibration of the PlusOptix PowerRef 3 with change in viewing distance, adult age and refractive error. Ophthalmic And Physiological Optics, 39(4), 7.
. (2016). Multifocal choroiditis with panuveitis in an 8-year-old boy with long-standing idiopathic acute anterior uveitis. European Journal Of Ophthalmology, 26. http://doi.org/10.5301/ejo.5000772 (Original work published 2016)
. (2014). Etanercept in Methotrexate-Resistant JIA-Related Uveitis. Seminars In Ophthalmology, 29. http://doi.org/10.3109/08820538.2013.839802 (Original work published 2014)
. (2014). Propranolol and periocular capillary hemangiomas: assessment of refractive effect. J Pediatr Ophthalmol Strabismusj Pediatr Ophthalmol Strabismus, 51, 165-70. (Original work published 2014)
. (2014). Comments on Infant Aphakia Treatment Study 4.5-Year Results. Jama Ophthalmology, 132. http://doi.org/10.1001/jamaophthalmol.2014.3532 (Original work published 2014)
. (08AD). Presentation of Suspected Pediatric Uveitis. Seminars In Ophthalmology, 29. http://doi.org/10.3109/08820538.2013.810288 (Original work published 08AD)
. (2013). Early diagnosis of Stargardt disease with multifocal electroretinogram in children. International Ophthalmology, 34. http://doi.org/10.1007/s10792-013-9812-9 (Original work published 2013)
. (09AD). Corneal endothelial dysfunction in Pearson syndrome. Ophthalmic Genetics, 34. http://doi.org/10.3109/13816810.2011.610862 (Original work published 09AD)
. (2010). Childhood sight impairment: a 10-year picture. Eye (Lond)Eye (Lond), 24, 112-7. (Original work published 2010)
. (2010). Web-StrabNet: A Web-Based Expert System for the Differential Diagnosis of Vertical Strabismus (Squint). Computational And Mathematical Methods In Medicinecomputational And Mathematical Methods In Medicine, 11, 89-97.
. (Oct-Dec). Pattern recognition of vertical strabismus using an artificial neural network (StrabNet). Strabismusstrabismus, 17, 131-8. (Original work published Oct-Dec)
. (2006). The repeatability of best corrected acuity in normal and amblyopic children 4 to 12 years of age. Invest Ophthalmol Vis Sciinvest Ophthalmol Vis Sci, 47, 614-9. (Original work published 2006)
. (Dec). Measurement of position acuity in strabismus and amblyopia: specificity of the vernier VEP paradigm. Invest Ophthalmol Vis Sciinvest Ophthalmol Vis Sci, 46, 4563-70. (Original work published Dec)
. (2004). Recovery of contour integration in relation to LogMAR visual acuity during treatment of amblyopia in children. Invest Ophthalmol Vis Sciinvest Ophthalmol Vis Sci, 45, 4016-22. (Original work published 2004)
. (2001). Contour Integration Deficits in Anisometropic Amblyopia. Invest Ophthalmol Vis Sciinvest Ophthalmol Vis Sci, 42, 875-878.
. (2000). A new test of contour integration deficits in patients with a history of disrupted binocular experience during visual development. Vision Resvision Res, 40, 1775-1783.
. (2000). Binocular Fixation Pattern and Visual Acuity in Children With Strabismic Amblyopia. Pediatric Ophthalmology And Strabismuspediatric Ophthalmology And Strabismus, 37, 24-28.
. (1999). Contour detection threshold: repeatability and learning with ‘contour cards’. Spatial Visionspatial Vision, 12, 257-266.
. (1991). Natural History of the Development of Visual Acuity in Infants. Eye (Lond)Eye (Lond), 5, 20-26.
. (1988). Preferential looking in clinical practice: a year's experience. Eye (Lond)Eye (Lond), 2 ( Pt 5), 488-95.
Presentations/Posters
. (2019). Reading in mild to moderate traumatic brain injury (mTBI). Journal of Vision.
Rehabilitation Engineering Research Center
The Center's research goal is to develop and apply new scientific knowledge and practical, cost-effective devices to understand and address better the real-world problems of blind, visually impaired, and deaf-blind consumers. The RERC has many ongoing R...
Patterns of Visual Deficits in Amblyopia
Background Amblyopia means blunted sight in the Greek language and is a term clinicians use to describe decreased vision usually in one eye most commonly due to a focusing error (refractive error in one...
CVI@SKI Meeting
We are a Smith-Kettlewell Eye Research Institute sponsored, Blind Babies Foundation supported research advocacy group consisting of SKI researchers, select clinicians, teachers of the visually impaired, and parents of children with cerebral visual impairment.
Higher Visual Function (HVF) in Individuals with Cerebral Visual Impairment (CVI)
Cerebral visual impairment often affects higher level visual function (HVF); for example, spatial attention, motion perception, divided attention, etc. Such impairments sometimes are not easy to detect by a routine vision test. Nevertheless, parents may observe abnormalities in the daily living...
Eye Movements and Accommodation Patterns in Strabismus
Strabismus misaligned eyes is a common developmental condition in young children that can lead to amblyopia or poor vision and other forms of low vision. This project looks at the eye movements in relation to accommodation or focusing power in these patients to determine predictors of strabismus and outcome of treatment, with the goal of improving early detection, intervention and treatment.
Investigating Reading in Individuals with Cerebral Visual Impairment (CVI)
There are many factors that can impair reading in CVI including, but not limited to, (i) increased crowding (ii) simultagnosia and (iii) abnormal eye movements. In this project, we aim to understand (i) how CVI affects reading, (ii) how current rehabilitation techniques or assistive technologies...
Reading in mTBI
People with mTBI often complain about dificulty in reading in spite of normal results in usual eye exams. We investigate this issue by looking at accommodation and reading rate and subjective measurement of reading difficuties for a variaty of reading tasks in normal and mTBI population. ...
Calibration of Eccentric Power Refractor
Eccentric power refractors need to be calibrated for accommodation and gaze position for individual participants. Calibration however can be time consuming. We look at different conditions in which calibration is necessary or preferable.
This project is now completed. Please see the...
Contact Information
Smith Kettlewell Eye Research Institute
2318 Filmore Street
San Francisco, California 94115
Email:
arvind@ski.org
Office Phone:
(415) 345-2083
Lab Phone:
(415) 510-1688
Links