Smith-Kettlewell Brain Imaging Center

Brain image with activated brain seen through a transparent skull

The Smith-Kettlewell Brain Imaging Center supports a wide variety of human brain imaging modalities, including MRI, MRI morphometry, functional MRI, fMR Iretonogrphy, fMRI dynamics, functional connectivity, Granger-causal connectivity, DTI, DTI tractography, whole-head EEG, EEG functional connectivity, ERG, EEG eye tracking, electroblepharography, etc. Our work centers on human visual neuroscience and computational vision, especially in the areas of human visual processing in adults, of the diagnosis of eye diseases and cortical deficits in infants and adults, on brain plasticity in relation to low vision and blindness, and on the processes of blindness rehabilitation. We are particularly interested in the normal capabilities of binocular visual processing and its disruption by forms of traumatic brain injury.

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Journal Articles
Likova, L. T., Mei, M., Mineff, K. N., & Nicholas, S. C.. (2019). Learning face perception without vision: Rebound learning effect and hemispheric differences in congenital vs late-onset blindness. Imaging Science And Technology: Human Vision And Electronic Imaging. http://doi.org/10.2352/ISSN.2470-1173.2019.12.HVEI-237 Human Vision and Electronic Imaging 2019
Karim, R., & Likova, L. T.. (2018). Haptic aesthetics in the blind: Behavioral and fMRI investigation. Imaging Science And Technology: Human Vision And Electronic Imaging, 532: 1-10. http://doi.org/DOI: 10.2352/ISSN.2470-1173.2018.14.HVEI-532
Likova, L. T., & Tyler, C. W.. (2018). When light hurts: Comparative morphometry of human brainstem in traumatic photalgia. Nature Scientific Reports, 8(1):6256. http://doi.org/doi: 10.1038/s41598-018-24386-z
Tyler, C. W., & Likova, L. T.. (Apr 2017). Studying the Retinal Source of Photophobia by Facial Electroretinography. Optometry And Vision Science, 94(4). http://doi.org/10.1097/OPX.0000000000001064 PMID: 28338564 (Original work published 2017)
Cacciamani, L., & Likova, L. T.. (2017). Memory-guided drawing training increases Granger causal influences from the perirhinal cortex to V1 in the blind. Neurobiology Of Learning And Memory, 141. http://doi.org/10.1016/j.nlm.2017.03.013 PMID: 28347878 PMCID: PMC 5488874 (Original work published 2017)
Cacciamani, L., & Likova, L. T.. (Apr 12 2016). Tactile object familiarity in the blind brain reveals the supramodal perceptual-mnemonic nature of the perirhinal cortex. Frontiers In Human Neuroscience, 10, 92. http://doi.org/ 10.3389/fnhum.2016.00092 PMID: 27148002 PMCID: PMC4828456 (Original work published 2016)
Presentations/Posters
Other Publications
Tyler, C. W., & Likova, L. T.. (2014). The neurometabolic underpinnings of fMRI BOLD dynamics. In Advanced Brain Neuroimaging Topics in Health and Disease-Methods and Applications:. InTech. http://doi.org/10.5772/58274

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  • Good Lab

    Our laboratory studies the conditions which cause monocular or bilateral blindness in infants and children.

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  • Photo of Steve Heinen

    Heinen Lab

    Our laboratory studies how visual perception and cognition guide the smooth pursuit eye movement system.

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  • Hou Lab

    Our research interests include investigating human visual cortex development and brain plasticity associated with amblyopia (lazy eye) and strabismus (misaligned eye

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  • Likova Lab

    The main areas of my research are learning and brain plasticity of multimodal sensorimotor processing in the blind and the sighted.

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  • Photo of Christopher Tyler

    Tyler Lab

    Our work centers on human visual neuroscience and computational vision, especially in the areas of stereoscopic depth, form, symmetry, and motion perception in adults, and the development of tests

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  • Verguese Lab

    Verghese Lab

    Our laboratory studies the mechanisms of healthy vision and action, as well as the basis of attention and visual adaptation in clinical populations.

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  • Oculomotor Control

    The binocular coordination of movements of the eyes is a complex issue controlled by many brainstem nuclei, and is subject to a wide variety of forms of disruption by traumatic brain injury and ocu

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