Smith-Kettlewell Brain Imaging Center
The Smith-Kettlewell Brain Imaging Center supports a wide variety of human brain imaging modalities, including MRI, MRI morphometry, functional MRI, fMR Iretonogrphy, fMRI dynamics, functional connectivity, Granger-causal connectivity, DTI, DTI tractography, whole-head EEG, EEG functional connectivity, ERG, EEG eye tracking, electroblepharography, etc. Our work centers on human visual neuroscience and computational vision, especially in the areas of human visual processing in adults, of the diagnosis of eye diseases and cortical deficits in infants and adults, on brain plasticity in relation to low vision and blindness, and on the processes of blindness rehabilitation. We are particularly interested in the normal capabilities of binocular visual processing and its disruption by forms of traumatic brain injury.
Tabs
Journal Articles
. (2020). Differences in the major fiber-tracts of people with congenital and acquired blindness. Imaging Science & Technology / Human Vision And Electronic Imaging 2020. Retrieved from https://doi.org/10.2352/ISSN.2470-1173.2020.11.HVEI-366
. (2019). Learning face perception without vision: Rebound learning effect and hemispheric differences in congenital vs late-onset blindness. Imaging Science And Technology: Human Vision And Electronic Imaging. http://doi.org/10.2352/ISSN.2470-1173.2019.12.HVEI-237 Human Vision and Electronic Imaging 2019
. (2018). When light hurts: Comparative morphometry of human brainstem in traumatic photalgia. Nature Scientific Reports, 8(1):6256. http://doi.org/doi: 10.1038/s41598-018-24386-z
. (2018). Haptic aesthetics in the blind: Behavioral and fMRI investigation. Imaging Science And Technology: Human Vision And Electronic Imaging, 532: 1-10. http://doi.org/DOI: 10.2352/ISSN.2470-1173.2018.14.HVEI-532
. (2018). Detection of amblyopia using sweep VEP Vernier and grating acuity. Investigative Ophthalmology & Visual Science, 59(1;59(3), 1435–1442.
. (2018). Fiber-tract differences in people with congenital and acquired blindness. Journal Of Vision, (18(10).
. (2018). Brain reorganization in adulthood underlying a rapid switch in handedness induced by training in memory-guided drawing. Neuroplasticity Ed. Chaban V. Retrieved from http://dx.doi.org/10.5772/intechopen.76317
. (Apr 2017). Studying the Retinal Source of Photophobia by Facial Electroretinography. Optometry And Vision Science, 94(4). http://doi.org/10.1097/OPX.0000000000001064 PMID: 28338564
. (2017). Memory-guided drawing training increases Granger causal influences from the perirhinal cortex to V1 in the blind. Neurobiology Of Learning And Memory, 141. http://doi.org/10.1016/j.nlm.2017.03.013 PMID: 28347878 PMCID: PMC 5488874
. (Apr 29 2016). Editorial:“Neural signal estimation in the human brain”. Frontiers In Neuroscience, 10, 185. http://doi.org/10.3389/fnins.2016.00185 PMID: 27199647 PMCID: PMC4850329
Conference Papers
. Face perception as a multisensory process. In Multisensory and Crossmodal Interactions, at IS&T HVEI. Multisensory and Crossmodal Interactions, at IS&T HVEI: Burlingame, California. Retrieved from https://www.imaging.org/site/IST/Conferences/EI/EI_2020/Conference/C_HVEI.aspx
Presentations/Posters
. (2020). Rapid training of supramodal spatial cognition and memory for improved navigation in low vision and blindness. ARVO Issue abstract 2020. ARVO 2020. Retrieved from https://iovs.arvojournals.org/article.aspx?articleid=2766791&resultClick=1
. (2019). Is the face schema innate? Evidence from learning faces in the congenital blind. Retrieved from SfN
. (2019). Top-down control of spatial memory visualization in early visual cortex. Retrieved from VSS, Fl
. (2018). Brain plasticity and art. Retrieved from Guangzhou Technology Institute
. (2018). Fiber-tract differences in people with congenital and acquired blindness. http://doi.org/10.1167/18.10.543
Other Publications
. (2014). The neurometabolic underpinnings of fMRI BOLD dynamics. In Advanced Brain Neuroimaging Topics in Health and Disease-Methods and Applications:. InTech. http://doi.org/10.5772/58274
. (2018). Memory drawing and learning in the class room. Retrieved from Southern China Normal University, Guangzhou
Upcoming Events
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Heinen Lab
Our laboratory studies eye movements to understand basic neural circuitry that moves the eyes for clear vision, and as a tool to probe mental processes that are distinctly human. Our ultimate goal is to understand the substrate of neurological function and dysfunction, leading to development of non-invasive diagnosis and therapy for brain trauma and psychiatric disorders.
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Likova Lab
The main areas of my research are learning and brain plasticity of multimodal sensorimotor processing in the blind and the sighted.
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Verghese Lab
Our laboratory studies the mechanisms of healthy vision and action, as well as the basis of attention and visual adaptation in clinical populations.
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Oculomotor Control
The binocular coordination of movements of the eyes is a complex issue controlled by many brainstem nuclei, and is subject to a wide variety of forms of disruption by traumatic brain injury and ocu
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Active
Study Title: Spectral ERG analysis of hypersensitivity to light in traumatic brain injury
The purpose of this research study is to use the spectral electroretinogram (ERG) to deteremine ho
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ActiveSL-CN: Harnessing the Power of Drawing for the Enhancement of Learning across Levels of Vision Function
This Science of Learning Collaborative Network brings together researchers and experts from th
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ActiveMechanisms of Photophobia in Mild Traumatic Brain Injury in Human Subjects: Therapeutic Implications
The purpose of this grant is to identify the mechanisms responsible for generating photophobia in p
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Completed
Advanced Spatiomotor Rehabilitation in Blindness and Visual Impairment
We propose a multidisciplinary approach to effective
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Current
- Christopher Tyler - Head, Smith-Kettlewell Brain Imaging Center
- Lora Likova - Likova Lab Director
- Spero Nicholas - Senior Programmer-Analyst