Smith-Kettlewell Brain Imaging Center

The Smith-Kettlewell Brain Imaging Center supports a wide variety of human brain imaging modalities, including MRI, MRI morphometry, functional MRI, fMR Iretonogrphy, fMRI dynamics, functional connectivity, Granger-causal connectivity, DTI, DTI tractography, whole-head EEG, EEG functional connectivity, ERG, EEG eye tracking, electroblepharography, etc. Our work centers on human visual neuroscience and computational vision, especially in the areas of human visual processing in adults, of the diagnosis of eye diseases and cortical deficits in infants and adults, on brain plasticity in relation to low vision and blindness, and on the processes of blindness rehabilitation. We are particularly interested in the normal capabilities of binocular visual processing and its disruption by forms of traumatic brain injury.
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Heinen Lab
Our laboratory studies eye movements to understand basic neural circuitry that moves the eyes for clear vision, and as a tool to probe mental processes that are distinctly human. Our ultimate goal is to understand the substrate of neurological function and dysfunction, leading to development of non-invasive diagnosis and therapy for brain trauma and psychiatric disorders.
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Likova Lab
The main areas of my research are learning and brain plasticity of multimodal sensorimotor processing in the blind and the sighted.
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Oculomotor Control
The binocular coordination of movements of the eyes is a complex issue controlled by many brainstem nuclei, and is subject to a wide variety of forms of disruption by traumatic brain injury and ocu
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Active
Spectral ERG analysis of hypersensitivity to light in traumatic brain injury
The purpose of this research study is to use the spectral electroretinogram (ERG) to deteremine ho
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Active
SL-CN: Harnessing the Power of Drawing for the Enhancement of Learning across Levels of Vision Function
This Science of Learning Collaborative Network brings together researchers and experts from th
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Active
Mechanisms of Photophobia in Mild Traumatic Brain Injury in Human Subjects: Therapeutic Implications
The purpose of this grant is to identify the mechanisms responsible for generating photophobia in patients who have suffered mild traumatic brain injury (mTBI). Currently, estimates indicate that this painful condition persists in about 60% of those who suffered from blast-related traumatic brain injury and 30% of those who suffered non-blast-related concussive injuries.
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Completed
Advanced Spatiomotor Rehabilitation in Blindness and Visual Impairment
We propose a multidisciplinary approach to effective spatiomotor rehabilitation in
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Completed
Stereoscopic motion-in-depth perception: fMRI and neurophysiological studies
This project is designed to adva
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Completed
Encoding of 3D Structure in the Visual Scene: A New Conceptualization
The multidisciplinary
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Completed
Human Oculomotor Functions & Their Deficits in Traumatic Brain Injury
Recent studies have established that a high proportion of patients diagnosed with mild (or diffuse)
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Completed
Learning in the Sighted and the Blind through Different Sensory Modalities: Structure and Dynamics of Cortical Reorganization
This project focuses on the emerging area of the neuroscience of art learning.
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- Christopher Tyler - Head, Smith-Kettlewell Brain Imaging Center
- Lora Likova - Likova Lab Director
- Spero Nicholas - Senior Programmer-Analyst