The research in my lab examines the neural processes, strategies and adaptations that humans use to interact with objects in the real world. We investigate these questions using psychophysics, eye movements, computational modeling and neuroimaging. Our goal is to understand the mechanisms of normal vision and action, as well as the basis of attention and visual adaptation in clinical populations. This work includes attention deficits in amblyopia, and the potential for binocular vision in individuals with age-related macular degeneration.
Tabs
Journal Articles
. (2021). Mapping the binocular scotoma in macular degeneration. Journal Of Vision, 21(3), 1-12. http://doi.org/https://doi.org/10.1167/jov.21.3.9
. (2020). Predicting stereopsis in macular degeneration. Journal Of Neuroscience. http://doi.org/10.1523/JNEUROSCI.0491-20.2020
. (2020). Contrast Normalization Accounts for Binocular Interactions in Human Striate and Extra-striate Visual Cortex. Journal Of Neuroscience, 40(13), 2753-2763.
. (2019). Motion perception in central field loss. Journal Of Vision, 19, 20–20. http://doi.org/10.1167/19.14.20
. (2019). The upper disparity limit increases gradually with eccentricity. Journal Of Vision, 19(11).
. (2019). The spatial and temporal properties of attentional selectivity for saccades and reaches. Journal Of Vision, 19(9):12.
. (2017). Latent Binocular Interactions in Cortical Area V1 of Human Amblyopia. Journal Of Vision, 17(10), 758-758. http://doi.org/10.1167/17.10.758
. (2017). Cortical sources of vernier acuity in the human visual system: an EEG source-imaging study. Journal Of Vision, 17(6).
. (2017). Attention to Multiple Objects Facilitates Their Integration in Prefrontal and Parietal Cortex. Journal Of Neuroscience, 37(19). http://doi.org/10.1523/JNEUROSCI.2370-16.2017
. (2017). Monocular and Binocular Smooth Pursuit in Central Field Loss. Vision Research.
. (2017). Texture segmentation influences the spatial profile of presaccadic attention. Journal Of Vision, 17(2).
. (2016). Accuracy of Eye Position for Saccades and Smooth Pursuit. Journal Of Vision, 16(23). http://doi.org/10.1167/16.15.23
. (2016). Training Eye Movements for Visual Search in Macular Degeneration. Journal Of Vision, 16(15).
. (2016). Smooth pursuit eye movements in patients with macular degeneration. Journal Of Vision, 16, 1.
. (2016). Degraded attentional modulation of cortical neural populations in strabismic amblyopia. Journal Of Vision, 16, 16.
. (2016). Degraded attentional modulation of cortical neural populations in strabismic amblyopia. Journal Of Vision, 16(3), 1–16.
. (2016). Depth Perception and Grasp in Central Field Loss. Investigative Ophthalmology & Visual Science, 57, 1476-87.
. (2015). Cortical sources of vernier acuity: an EEG-source imaging study. Journal Of Vision, 15, 1004.
. (2015). Stop before you saccade: Looking into an artificial peripheral scotoma. Journal Of Vision, 15, 7.
. (2014). The influence of segmentation and uncertainty on target selection. Journal Of Vision, 14, 3.
. (2013). Attentional modulation: target selection, active search and cognitive processing. Vision Research, 85, 1-4.
. (2012). Attention selects informative neural populations in human V1. The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience, 32, 16379-90.
. (2012). The selectivity of task-dependent attention varies with surrounding context. The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience, 32, 12180-91.
. (2009). Peeling plaids apart: context counteracts cross-orientation contrast masking. Plos One, 4, e8123.
. (2009). Visual attention: Neurophysiology, psychophysics and cognitive neuroscience. Vision Research, 49, 1033-6.
. (2007). Orientation discrimination in the periphery depends on the context. Journal Of Vision, 7, 585–585.
. (2005). An information maximization model of eye movements. Advances In Neural Information Processing Systems, 17, 1121-8.
. (2005). Attention to locations and features: different top-down modulation of detector weights. Journal Of Vision, 5, 556-70.
. (2005). Predictability and the dynamics of position processing in the flash-lag effect. Perception, 34, 31-44.
. (2002). Contour completion through depth interferes with stereoacuity. Vision Research, 42, 2153-162.
. (2002). Integration of speed signals in the direction of motion. Perception & Psychophysics, 64, 996-1007.
. (2002). The unique criterion constraint: a false alarm?. Nature Neuroscience, 5, 707; author reply 707-8.
. (2000). Stimulus configuration determines the detectability of motion signals in noise. Journal Of The Optical Society Of America. A, Optics, Image Science, And Vision, 17, 1525-34.
. (1999). Local motion detectors cannot account for the detectability of an extended trajectory in noise. Vision Research, 39, 19-30.
. Predicting Stereopsis in Macular Degeneration. Journal Of Neuroscience.
Presentations/Posters
. (2020). Do saccade characteristics in macular degeneration adapt to compensate for the binocular scotoma?. Date Published 09/2020, Bay Area Vision Research Day: Online.
. (2020). Effects of task demands on smooth pursuit gain in macular degeneration. Investigative Ophthalmology & Visual Science. Association for Research in Vision and Ophthalmology Annual Meeting: Canceled due to COVID.
. (2019). Mapping the binocular scotoma in macular degeneration. Bay Area Vision Research Day.
. (2019). Binocular scotoma mapping and eye movement patterns in central field loss. Gordon Research Conference on Eye Movements. Lewiston, USA: Lewiston, USA.
. (2019). Motion Perception in Central Field Loss: Visual Field Contributions. Investigative Ophthalmology & Visual Science. ARVO: Vancouver B.C.
. (2019). Does eccentric fixation alter head movement strategy for smooth pursuit?. Neural Control of Movement: Toyama, Japan.
. (2018). Interaction of Eye and Head Movements during Smooth Pursuit in Macular Degeneration. Investigative Ophthalmology & Visual Science.
. (2018). Motion Perception in Central Field Loss.
. (2016). Gaze Changes from Binocular to Monocular Viewing during Smooth Pursuit in Macular Degeneration. Investigative Ophthalmology & Visual Science.
. (2016). Do we foveate targets during smooth pursuit?.
. (2015). Evaluation of Smooth Pursuit in Individuals with Central Field Loss. European Conference on Eye Movements. Vienna, Austria: Vienna, Austria.
. (2015). Feedback about gaze position improves saccade efficiency. Journal of vision.
. (2013). Immediate feedback improves saccadic efficiency. Journal of Vision. Association for Research in Vision and Ophthalmology.
Other Publications
. (2015). The Efficiency of Vision and Action. (). http://doi.org/10.1016/j.visres.2015.06.003
Active
Active
Stereopsis in Macular Degeneration
Macular degeneration affects the central retina, often causing asymmetrical damage to the two eyes. How does this asymmetrical loss affect stereopsis — the percept of depth generated by the small separation of image features in the two eyes?
Active
Tracking a target in depth with central field loss
Bilateral field loss due to maculopathy creates a scotoma that extends in depth — a volume scotoma. Morevoer the size of the scotoma depends on whether observers turn their eyes to track a target as it comes closer. This project investigates how the volume scotoma affects the ability to track oncoming targets in these individuals, and in controls with a simulated volume scotoma.
Active
Postdoctoral Training in Vision Research
The Smith-Kettlewell Eye Research Institute (SKERI) is an NEI Institutional Training Grant Awardee. The grant was awarded to provide postdoctoral training in basic and clinical science relevant to translational vision research and rehabilitation.
Active
Motion Perception in Central Field Loss
The project investigates motion perception in individuals with vision loss due to central retinal lesion, but who retain healthy peripheral retina. Healthy peripheral retina is exquisitely sensitive to fast speeds, however, there is limited and conflicting information about motion processing in...
Active
Adaptive Visual Strategies for Individuals with Macular Degeneration
In this project we try to gain a better understanding of what visual strategies people use to gather information in the world.
Active
Fovea Use During Smooth Pursuit
There is continuing debate as to whether smooth pursuit relies on the foveation of a moving target, especially when the target is compact. Previous studies have shown that gaze is placed on the center-of-mass of a target during saccadic eye movements. This research aims to understand whether eye...
Active
Characteristics of Smooth Pursuit in Individuals with Central Field Loss
This project investigates the properties of smooth pursuit eye movements in individuals with macular degeneration. Commonly believed to be a fovea-linked eye movement, smooth pursuit has not been previously investigated in individuals with central field loss, despite its importance for tracking moving objects, such as vehicles or pedestrians on a busy street.
Active
Eye-Hand coordination in Central Field Loss
Eye-hand coordination in AMD
Active
Modeling Smooth Pursuit Eye-Movement Deficits in Macular Degeneration
The project investigates the deficits in smooth pursuit in individuals with age-related macular degeneration within the framework of a Bayesian model.
Active
Coordination of Eye and Head Movements in Central Field Loss
This project investigates the interaction between central field loss (CFL) and vestibular function.
Completed
Completed
Upper Depth Limit Across Visual Field
Stereopsis is important for tasks of daily living such as eye-hand coordination. It is best in central vision but is also mediated by the periphery. Previously we have shown that individuals with central-field loss who have residual stereopsis in the periphery perform better at an eye-hand-coordination task. Here we sought to determine what sets the limit of stereopsis, defined as the largest disparity that supports the sustained appearance of depth, in the near periphery in healthy individuals. We used a rigorous method to determine the uppermost limit of disparity. The disparity limit is the point at which the threshold for judging dichoptic separation between the half-images is equal to the monocular width-discrimination threshold. The disparity limit at 10° was a factor of 2–4 times larger than the fovea, regardless of the meridian tested. The increase in the disparity limit with eccentricity was shallow, similar to that of Panum's area. Within this disparity limit, disparity increment thresholds were comparable for foveal and peripheral targets, illustrating the significance and utility of peripheral stereopsis, especially in the absence of foveal stereopsis.
Completed
Novel Method to Teach Scotoma Awareness
This project aims to improve visual function in individuals with age-related macular degeneration (AMD). AMD isassociated with central field loss that cannot be corrected optically. Individuals with AMD are often unaware of their scotoma and their eye movements follow more random patterns,...
Completed
Strategies for Efficient Visual Information Gathering
Active visual search
Completed
Target Selection in the Real World
Attention and Segmentation
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