Our laboratory studies the conditions which cause monocular or bilateral blindness in infants and children.
Smith-Kettlewell Brain Imaging CenterView Center
The Smith-Kettlewell Brain Imaging Center supports a wide variety of human brain imaging modalities, including MRI, MRI morphometry, functional MRI, fMR Iretonogrphy, fMRI dynamics, functional connectivity, Granger-causal connectivity, DTI, DTI tractography, whole-head EEG, EEG functional connectivity, ERG, EEG eye tracking, electroblepharography, etc. Our work centers on human visual neuroscience and computational vision, especially in the areas of human visual processing in adults, of the diagnosis of eye diseases and cortical deficits in infants and adults, on brain plasticity in relation to low vision and blindness, and on the processes of blindness rehabilitation. We are particularly interested in the normal capabilities of binocular visual processing and its disruption by forms of traumatic brain injury.
Neonatal Jaundice and Vision Loss
High concentrations of unconjugated bilirubin are neurotoxic and cause brain damage in newborn infants. However, the exact level of bilirubin that may be neurotoxic in a given infant is unknown.
Visual Cortical Function in Very Low Birth Weight Infants
Preterm infants are at high risk of visual and neural developmental deficits. We used swept parameter visual evoked potential (sVEP) to determine whether premature birth alters visual cortical function.