Contour Integration Deficits in Anisometropic Amblyopia

Journal Article


PURPOSE. Previous retrospective studies have found that inte- gration of orientation information along contours defined by Gabor patches is abnormal in strabismic, but not in anisome- tropic, amblyopia. This study was conducted to reexamine the question of whether anisometropic amblyopes have contour integration deficits prospectively in an untreated sample, to isolate the effects of the disease from the effects of prior treatment—factors that may have confounded the results in previous retrospective studies.
METHODS. Contour detection thresholds, optotype acuity, and stereoacuity were measured in a group of 19 newly diagnosed anisometropic amblyopes before initiation of occlusion ther- apy. Contour detection thresholds were measured using a card-based procedure.
RESULTS. Significant interocular differences in contour detec- tion thresholds were present in 14 of the 19 patients with anisometropic amblyopia.
CONCLUSIONS. Contour integration deficits are a common, but not universal, finding in untreated anisometropic amblyopia. Differences in the prevalence of contour integration deficits between the present study and that of another study may lie in differences in treatment history and/or in the sensitivity of the two different contour integration tasks.


Invest Ophthalmol Vis SciInvest Ophthalmol Vis Sci



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